A total of 1918 loci, detected by the hybridization of 938 expressed sequence tag unigenes from 26 Triticeae cDNA libraries, were mapped to wheat homoeologous group 4 chromosomes using a set of deletion, ditelosomic, and nulli-tetrasomic lines. The 1918 EST loci were not distributed uniformly among the three group 4 chromosomes; 41, 28, and 31% mapped to chromosomes 4A, 4B, and 4D, respectively. This pattern is in contrast to the cumulative results of EST mapping in all homoeologous groups, as reported (...) elsewhere, that found the highest proportion of loci mapped to the B genome. Sixty-five percent of these 1918 loci mapped to the long arms of homoeologous group 4 chromosomes, while 35% mapped to the short arms. The distal regions of chromosome arms showed higher numbers of loci than the proximal regions, with the exception of 4DL. This study confirmed the complex structure of chromosome 4A that contains two reciprocal translocations and two inversions, previously identified. An additional inversion in the centromeric region of 4A was revealed. A consensus map for homoeologous group 4 was developed from 119 ESTs unique to group 4. Forty-nine percent of these ESTs were found to be homoologous to sequences on rice chromosome 3, 12% had matches with sequences on other rice chromosomes, and 39% had no matches with rice sequences at all. Limited homology was found between wheat ESTs on homoeologous group 4 and the Arabidopsis genome. Forty-two percent of the homoeologous group 4 ESTs could be classified into functional categories on the basis of blastX searches against all protein databases. (shrink)

Thirty-two years ago W. V. Quine proposed a definition of 'logical truth' that has been widely repeated and reprinted. Quine himself seems to have recognized that this definition is wrong in detail; in section 1 we eliminate this fault. What has perhaps been less widely observed is that, in abandoning the model-theoretic account of logical truth in favor of a "substitutional" account, Quine's definition swells the ranks of the logical truths and makes the classification of a sentence as a logical (...) truth dependent both on the interpretation of its extralogical words and on the extralogical vocabulary available in the language. (shrink)

Identity construction — the process of creating and building a new future self — is an integral part of a person’s professional career development. However, at present we have little understanding of the psychological mechanisms that underpin this process. Likewise, we have little understanding of the barriers that obstruct it, and which thus may contribute to inequality in career outcomes. Using a social identity lens, and particularly the Social Identity Model of Identity Change (SIMIC), we explore the process of academic (...) identity construction among doctoral students. Through thematic analysis of semi-structured interviews with 22 PhD candidates, we observe that the identity construction process relies on a person’s perception of a navigable pathway between their current self and their future self. Importantly, participants who were able to access multiple identity resources were more likely to perceive a navigable pathway to a future professional self (e.g., as an academic), unless they perceived these identities to be incompatible with those held by leading members of the profession (e.g., their supervisors). This research suggests that the identities that people are able to access as they progress in their careers may play an important role in their ongoing professional identity construction and career success. (shrink)

Background The use of lengthy, detailed, and complex informed consent forms is of paramount concern in biomedical research as it may not truly promote the rights and interests of research participants. The extent of information in ICFs has been the subject of debates for decades; however, no clear guidance is given. Thus, the objective of this study was to determine the perspectives of research participants about the type and extent of information they need when they are invited to participate in (...) biomedical research. Methods This multi-center, cross-sectional, descriptive survey was conducted at 54 study sites in seven Asia-Pacific countries. A modified Likert-scale questionnaire was used to determine the importance of each element in the ICF among research participants of a biomedical study, with an anchored rating scale from 1 to 5. Results Of the 2484 questionnaires distributed, 2113 were returned. The majority of respondents considered most elements required in the ICF to be ‘moderately important’ to ‘very important’ for their decision making. Major foreseeable risk, direct benefit, and common adverse effects of the intervention were considered to be of most concerned elements in the ICF. Conclusions Research participants would like to be informed of the ICF elements required by ethical guidelines and regulations; however, the importance of each element varied, e.g., risk and benefit associated with research participants were considered to be more important than the general nature or technical details of research. Using a participant-oriented approach by providing more details of the participant-interested elements while avoiding unnecessarily lengthy details of other less important elements would enhance the quality of the ICF. (shrink)

Comments on G. Marcus' criticisms (see record 1996-24670-001) of K. Plunkett's and V. Marcham's (see record 1994-35650-001) connectionist account of the acquisition of the English past tense (verb morphology). The original model is reviewed. Graphing, overregularization, and other criticisms are addressed (PsycINFO Database Record (c) 2000 APA, all rights reserved).

Reminiscences of Peter, by P. Oppenheim.--Natural kinds, by W. V. Quine.--Inductive independence and the paradoxes of confirmation, by J. Hintikka.--Partial entailment as a basis for inductive logic, by W. C. Salmon.--Are there non-deductive logics?, by W. Sellars.--Statistical explanation vs. statistical inference, by R. C. Jeffre--Newcomb's problem and two principles of choice, by R. Nozick.--The meaning of time, by A. Grünbaum.--Lawfulness as mind-dependent, by N. Rescher.--Events and their descriptions: some considerations, by J. Kim.--The individuation of events, by D. Davidson.--On properties, by (...) H. Putnam.--A method for avoiding the Curry paradox, by F. B. Fitch.--Publications (1934-1969) by Carl G. Hempel (p. [266]-270). (shrink)

Objective The aim of this study was to examine the development of the implementation of patient rights and the practical course of patient rights legislation in Edirne, as well as the verbal and written applications to relevant departments between 2004 and 2008. Methods The present study was a descriptive, retrospective and cross-sectional study. The data of the study were obtained by retrospectively reviewing records of written complaints to patient rights units and on-site solutions between 2004, the year of establishment of (...) these units, and 2008. Results The incidence of written and verbal complaints were calculated to be 23.1 in 100 000 and 137.9 in 100 000, respectively. The increase was 102.2% for on-site solutions, whereas it was calculated as 97.8% for written applications. It was noticed that the rate of violation judgements was high (42.5% (17/40)) in the first year the Edirne State Hospital patient rights committee was established. Conclusions Possible problems encountered during the presentation of health services can be solved by the implementation of patient rights under the legislative guarantee. The implementation of patient rights should be considered as reflections of a socialised government on health services. (shrink)

According to Proudhon, before Kant, the believer and the philosopher moved “by an irresistible impulse,” asked themselves, “What is God!” They then asked themselves “Which, of all religions, is the best!” “In fact, if there does exist a Being superior to Humanity, there must also exist a system of the relations between this Being and Humanity. What then is this system! The search for the best religion is the second step that the human mind takes in reason and in faith. (...) Kant gave up these insolvable questions. He no longer asked himself what is God, and which is the best religion; he set about explaining the origin and development of the Idea of God; he undertook to work out the biography of this idea.” And the results he attained were as great as they were unexpected. “What we seek, what we see, in God, as Malebranche said ... is our own Ideal, the pure essence of Humanity ... The human soul does not become conscious of its Ego through premeditated contemplation, as the psychologists put it; the soul perceives something outside itself, as if it were a different Being face to face with itself, and it is this inverted image which it calls God. Thus morality, justice, order, law, are no longer things revealed from above, imposed upon our free will by a socalled Creator, unknown and ununderstandable; they are things that are proper and essential to us as our faculties and our organs, as our flesh and our blood. In two words religion and society are synonymous terms, man is as sacred to himself as if he were God.”. (shrink)

Предназначено для представителей науки и образования, политических партий, общественных и религиозных организаций, органов государственного управления.

Автор бросает вызов с одной стороны как материалистической, так и идеалистической философии прошлого и настоящего, с другой - канонической космологической теории Большого взрыва, основанной на принципах механицизма, присущего естествознанию наших дней.